Depressive episodes are ridiculously painful and sadly an inescapable part of the illness he suffered from; in this case, apparently it was terminal. I wish the best for his family in this dark time. So many people loved him and he touched so many of us with his work. It's a tremendous loss. I saw him working in person once, around the time this photo was taken (not at E3 but on the set of Death to Smoochy). Incredible guy, everything you'd hope for and more.