That's exactly the vibe I get when I see Dave crowing about what a "feminist" he is, and bragging about how he was friends with that transgender comedian, and how that seemingly makes him absolutely NOT sexist or transphobic or homophobic in any way, which is the equivalent of "some of my best friends are black."
He says that Daphne finally yelled to him that she wanted to be seen as a human being (paraphrasing), and he understood because he wanted that for himself, too; but he spent the entire schtick treating them like they were less than humans and wondering why they're pissed off at him.
Watching Dave say "gender is a 'fact' and then talking about sex parts just demonstrates Dave's ignorance about any of this stuff (ditto for the Harry Potter chick).